What is the infusion process for tPA in stroke treatment?

The correct infusion process for tPA (tissue Plasminogen Activator) in the treatment of stroke involves administering a 1-minute bolus, followed by an infusion over 60 minutes. This method is essential for achieving the appropriate therapeutic levels of the medication while minimizing the risk of complications. After the infusion is completed, a normal saline (NSS) flush is typically performed to ensure that the full dose of tPA is delivered into the vascular system.

This method of administration is established based on clinical protocols aimed at maximizing the efficacy of the drug in dissolving the clot responsible for the stroke, thereby restoring blood flow to the affected brain area. It is critical to adhere to this regimen to ensure patient safety and the effectiveness of the treatment.