What is the recommended duration for bolusing TNK?

The recommended duration for bolusing TNK (Tenecteplase) is 5 seconds. This rapid administration is critical in the context of thrombolytic therapy for acute ischemic stroke. The quick bolus allows the medication to enter the bloodstream promptly, which facilitates faster action to dissolve the clot obstructing blood flow to the brain. Timely intervention is vital in stroke management to improve patient outcomes and reduce the risk of long-term disability.

Other durations, while they could function in different medical contexts, are not aligned with the established guidelines for TNK administration in stroke care. The 5-second bolus is a specific recommendation supported by clinical studies aimed at enhancing the effectiveness of thrombolytic therapy while minimizing the time to treatment—a crucial factor in stroke management.